Luís has fronted campaigns for major international brands such as Benetton, Paul Smith, Etro, Tom Ford, and Tommy Hilfiger, which led to his inclusion in models.com’s Top 50 Male Models in the World. He also walked the runway for iconic fashion houses like YSL, Dior, Hermès, and Jean Paul Gaultier at fashion weeks in Paris, Milan, London, New York City, and Lisbon. He has received several awards, including the Golden Globe for Best Male Model in 2011, and the Fashion TV Awards for Best Male Model in 2010 and Male Fashion Personality in 2011. In 2021, Luís became the first man to star in a Christian Louboutin Beauty campaign. That same year, he launched his own jewelry brand — originally named Call Me Gorgeous and now known as Fucking Gorgeous — with collections presented at ModaLisboa. He also appeared as host and mentor on the TV show Cabelo Pantene – O Sonho on TVI.